8 Dog Breeds With The Most Disease-Causing Genetic Variants
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The dog breeds that are most likely to carry disease-causing genetic mutations have been revealed, with Cavalier King Charles Spaniels unfortunately taking the top spot.
According to new research conducted by Uppsala University in Sweden, the small lap dogs have sadly been negatively affected by years of inbreeding and are now at higher risk of heart disease. In fact, scientists found the breed has genetic variants linked to myxomatous mitral valve disease (MMVD) — the most common acquired heart disease in small breed dogs.
Erik Axelsson, who published the findings in the journal PLOS Genetics, said years of breeding has caused many dogs to inherit genetic diseases.
“We find that individuals belonging to the breed affected by the most intense breeding – Cavalier King Charles Spaniel (cKCs) – carry more harmful variants than other breeds,” he said in the paper. “[This indicates] that past